2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1093R
    Fenchlorphos (Standard)
    		Inhibitor
    Fenchlorphos (Standard) is the analytical standard of Fenchlorphos. This product is intended for research and analytical applications. Fenchlorphos, an organophosphate, is an insecticide. Fenchlorphos is an inhibitor of the enzyme acetylcholinesterase (AChE). Fenchlorphos is able to cause mitochondrial dysfunction.
    Fenchlorphos (Standard)
  • HY-W004546R
    Abametapir (Standard)
    		Inhibitor
    Abametapir (Standard) is the analytical standard of Abametapir. This product is intended for research and analytical applications. Abametapir is a metalloproteinase (MMP) inhibitor which is able to target metalloproteinases critical to egg hatching and louse development. Abametapir can inhibit hatching of both head and body louse.
    Abametapir (Standard)
  • HY-170848
    Antimalarial agent 48
    		Inhibitor
    Antimalarial agent 48 (Compound 15a) is a triazine-class compound with antimalarial activity, showing inhibitory concentrations of 280 nM against Plasmodium falciparum K1 and 290 nM against Plasmodium falciparum FCR3. Antimalarial agent 48 is expected to be useful for research in the field of antimalarial infections.
    Antimalarial agent 48
  • HY-172207
    POPTc80-IN-1
    		Inhibitor
    POPTc80-IN-1 (Compound LC-45) is a competitive inhibitor for prolyl oligopeptidase of Trypanosoma cruzi POPTc80 with an IC50 of 0.23 μM and a Ki of 0.054 μM. POPTc80-IN-1 inhibits the invasion of T. cruzi into host cell with an IC50 of 46.71 μM.
    POPTc80-IN-1
  • HY-158818
    DXR-IN-2
    		Inhibitor
    DXR-IN-2 is a 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) inhibitor and an antimalarial agent (IC50: 0.1062 μM for Plasmodium falciparum DXR and 0.369 μM for Plasmodium falciparum). DXR-IN-2 inhibits Plasmodium falciparum growth by suppressing the methyl erythritol phosphate (MEP) pathway via DXR.
    DXR-IN-2
  • HY-23317
    N-Methyl-4-(8-phenoxyoctoxy)aniline
    		Inhibitor
    N-Methyl-4-(8-phenoxyoctoxy) aniline (Compound 3568) is an anti-schistosomal agent. N-Methyl-4-(8-phenoxyoctoxy) aniline exhibits definite anti-Schistosoma mansoni activity in mouse models, but has high acute toxicity. N-Methyl-4-(8-phenoxyoctoxy) aniline can be used in studies related to schistosomiasis.
    N-Methyl-4-(8-phenoxyoctoxy)aniline
  • HY-W654156
    Diclazuril-13C3,15N2
    		Inhibitor
    Diclazuril-13C3,15N2 is 13C and 15N labeled Diclazuril. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al.
    Diclazuril-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-B0244R
    Praziquantel (Standard)
    		Inhibitor
    Praziquantel (Standard) is the analytical standard of Praziquantel. This product is intended for research and analytical applications. Praziquantel is a broadly effective trematocide and cestocide, the initial effect of praziquantel on the schistosome may be an interaction of the drug with lipid constituents of the tegumental membrane. Praziquantel is used for the research of schistosomiasis.
    Praziquantel (Standard)
  • HY-128663
    GLK7-001
    		Inhibitor
    GLK7-001 is a Trypanosoma cruzi glucokinase (TcGlcK) inhibitor. GLK7-001 has in vitro trypanocidal activity.
    GLK7-001
  • HY-180373
    WR 30090
    		Inhibitor
    WR 30090 (Compound 37) is a broad-spectrum antimalarial agent that does not rely on the classical antifolate pathway. WR 30090 exhibits strong activity against a variety of chloroquine-sensitive and resistant Plasmodium falciparum strains, especially the highly resistant Vietnamese strain. WR 30090 shows high activity in mouse malaria tests, with a minimum effective dose of 5 mg/kg and a minimum cure dose of 20 mg/kg. WR 30090 can be used for research on acute malaria.
    WR 30090
  • HY-B0147AR
    Pefloxacin mesylate (Standard)
    		Inhibitor
    Pefloxacin mesylate (Standard) (Pefloxacinium mesylate (Standard)) is the analytical standard of Pefloxacin mesylate (HY-B0147A). This product is intended for research and analytical applications. Pefloxacin (Pefloxacinium) mesylate is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin mesylate inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin mesylate exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin mesylate has anti-Plasmodium yoelii infection activity. Pefloxacin mesylate increase UVA-induced edema and immunesuppression. Pefloxacin mesylate can be used for infection studies.
    Pefloxacin mesylate (Standard)
  • HY-170840
    Antimalarial agent 47
    		Inhibitor
    Antimalarial agent 47 (compound F14) is an antimalarial compound, with an IC50 of 235 nM for the Plasmodium falciparum W2 strain.
    Antimalarial agent 47
  • HY-125596
    Lachnumon
    		Inhibitor
    Lachnumon is a fungal metabolite with nematicidal and antimicrobial activities.
    Lachnumon
  • HY-178456
    Antileishmanial agent-36
    		Inhibitor
    Antileishmanial agent-36 (compound 4f) is an indole-dihydropyrimidinone derivative with anti-leishmanial activity. Antileishmanial agent-36 induces reactive oxygen species (ROS)-mediated mitochondrial dysfunction and apoptosis. Antileishmanial agent-36 exhibits potent activity against L. donovani (IC50 =4.54 μM) with low cytotoxicity against J774.1 macrophage. Antileishmanial agent-36 clears the parasite burden in a visceral leishmaniasis (VL) model. Antileishmanial agent-36 can be used for VL research.
    Antileishmanial agent-36
  • HY-149697
    Insecticidal agent 6
    		Inhibitor
    Insecticidal agent 6 (Compound Im) is an insect ryanodine receptors (RyRs) inhibitor, with an EC50 value of 0.6308 µM against S. frugiperda RyRs. Insecticidal agent 6 has excellent insecticidal activity against lepidopteran pests and can be used for research on pests and diseases.
    Insecticidal agent 6
  • HY-B1322BR
    Amodiaquine dihydrochloride (Standard)
    		Inhibitor
    Amodiaquine (dihydrochloride) (Standard) is the analytical standard of Amodiaquine (dihydrochloride). This product is intended for research and analytical applications. Amodiaquine dihydrochloride (Amodiaquin dihydrochloride), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor with a Ki of 18.6 nM. Amodiaquine dihydrochloride is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect.
    Amodiaquine dihydrochloride (Standard)
  • HY-170219
    RMM23
    		Inhibitor
    RMM23 is an inhibitor targeting PfBDP1 with a Kd value of 1.24 μM. RMM23 against the wild-type strains 3D7 and NF54, and the multidrug-resistant K1 strain in vitro blood stage, with EC50 values of 18 μM, 14 μM, 20 μM, respectively .
    RMM23
  • HY-180833
    Antileishmanial agent-39
    		Inhibitor
    Antileishmanial agent-39 (Compound 4h) is an antileishmanial agent. Antileishmanial agent-39 shows antileishmanial activity against the axenic amastigote form of Leishmania infantum with an IC50 of 0.42 μM.
    Antileishmanial agent-39
  • HY-180943
    Antiparasitic agent-39
    		Inhibitor
    Antiparasitic agent-39 (Compound 14) is a selective antiparasitic agent and Deferasirox (HY-17359) derivative. Antiparasitic agent-39 reduces the mitochondrial membrane potential. Antiparasitic agent-39 shows antiparasitic activity against T. brucei, T. gambiense, L. Mexicana, T. gondii, B. divergens, P. falciparum with EC50s of 4.2 nM, 10.4 nM, 52.0 nM, 17.0 nM, 41.2 nM, 54.8 nM, respectively.
    Antiparasitic agent-39
  • HY-101715R
    Panidazole (Standard)
    		Inhibitor
    Panidazole (Standard) is the analytical standard of Panidazole (HY-101715). This product is intended for research and analytical applications. Panidazole is an amoebicide.
    Panidazole (Standard)
Parasite Isoform Comparison

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